| 几种与肿瘤血管生成有关的调控因子研究进展 |
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| 引用本文： | 欧阳逸斌徐明.几种与肿瘤血管生成有关的调控因子研究进展[J].现代生物医学进展,2012,12(21):4176-4179. |
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| 作者姓名： | 欧阳逸斌徐明 |
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| 作者单位： | 中南大学分子药物与治疗研究所 湖南长沙410078 |
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| 基金项目： | 湖南省人事厅留学人员择优资助项目(394201001) |
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| 摘 要： | 肿瘤血管能够导致肿瘤疯狂生长,也是肿瘤细胞扩散和转移的秘密通道。因此对肿瘤血管的生成的研究就成为了当前研究的热点。本文对VEGF、MMP、EGFR、bFGF等重要的促血管生成因子与肿瘤血管生成、生长关系的临床证明、病理组织学研究、基因学研究以及以此为靶点的药物治疗的研究现状,尤其是中药治疗研究情况作综述。
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| 关 键 词： | 肿瘤血管 VEGF MMP EGFR bFGF |
Progress of Studies on Several Regulatory Factors Related to Tumor
Angiogenesis |
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| OUYANG Yi-bin,XU Ming.Progress of Studies on Several Regulatory Factors Related to Tumor
Angiogenesis[J].Progress in Modern Biomedicine,2012,12(21):4176-4179. |
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| Authors: | OUYANG Yi-bin XU Ming |
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| Institution: | △(Research Institute for Molecular Pharmacology and Therapeutics,Central South University,Hunan Changsha 410078,China) |
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| Abstract: | Tumor vascular can lead to the crazy growth of tumor,and is also the secret tunnels of cancer cells to spread and transfer.So study on the generation of tumor vascular become the hot spot of current research.We will review the studies of the rela-tionship between some important angiogenesis factors like,VEGF,MMP,EGFR,bFGF with tumor vascular production and development from different aspects,and the studies of the drug therapy to these therapeutic targets,especially Chinese traditional medicine. |
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| Keywords: | Tumor vascular VEGF MMP EGFR bFGF |
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