金龙胶囊联合化疗治疗晚期非小细胞肺癌临床疗效观察

目的:观察金龙胶囊联合化疗与单纯化疗对晚期肺小细胞癌患者的疗效、生活质量等因素的影响。方法:将99例患有晚期非小细胞肺癌患者随机分为两组:治疗组,在NP化疗方案基础上加服金龙胶囊治疗;对照组,单纯接受NP方案化疗。对99例患者追踪2个月,观察并比较患者的疗效、体质量、生活质量、毒副反应等方面的差异。结果:在NP化疗方案基础上加服金龙胶囊治疗在患者疗效评价方面与单纯NP方案化疗相比不具有统计学差异(P>0.05);在提高患者体质量、改善患者临床症状和生活质量等方面均优于单纯NP方案化疗(P<0.05);在化疗所引发的白细胞、血红蛋白和血小板降低等部分毒副反应发生率方面低于单纯NP方案化疗组(P<0.05)。结论:金龙胶囊联合NP化疗治疗晚期非小细胞肺癌不仅可以起到化疗增效的作用,而且能够明显提高患者生活质量,有效的改善临床症候,降低化疗引发的毒副反应,这一联合治疗方案可以在临床治疗中广泛推广。

Jin Long Capsule Combined with NP Chemotherapy in the Treatment of Advanced NSCLC Patients

Objective: To observe the differences between pure chemotherapy and Jin Long capsule combination with chemotherapy treatment for patients’ therapeutic effect and the quality of life with advanced non-small cell lung cancer(NSCLC) patients.Methods: 99 cases advanced NSCLC patients were randomly divided into chemotherapy group and Jin Long capsule combination with chemotherapy group.Chemotherapy group was treated with NP scheme(vinorelbine,NVB and cis-platinum,DDP).At the same time,the other group was treated with Jin Long capsule and NP scheme.All patients were observed for two months and analyzed the differences in the thera-peutic effect score,body quality score,quality of life score and toxic effect.Results: Jin Long capsule combination with NP scheme is su-perior to NP scheme in the improvement of body quality score,quality of life score and the decrease of toxic effect(P< 0.05).However,the combined scheme is not better than NP scheme in the improvement of therapeutic effect score(P>0.05).Conclusion: Jin Long cap-sule combination with NP scheme could improve the life quality and body quality of the patients and decrease the incidence of toxic ef-fect induced by chemotherapy.