电针神经刺激疗法联合盆底肌训练对早期宫颈癌广泛性全子宫切除术后患者尿潴留、膀胱功能和免疫功能的影响

摘要 目的：观察电针神经刺激疗法联合盆底肌训练在早期宫颈癌广泛性全子宫切除术后康复中的应用价值。方法：前瞻性收集我院2020年3月~2021年10月期间收治的早期宫颈癌广泛性全子宫切除术患者98例，采用随机数字表法分为研究组和对照组各49例，对照组患者指导其进行盆底肌训练，研究组患者则在盆底肌训练的基础上加以电针神经刺激疗法，对比两组尿潴留发生率以及膀胱功能、免疫功能、盆底功能恢复情况。结果：术后13周时评估结果显示，研究组的盆底肌综合肌力测定正常率高于对照组（P<0.05）。两组术后13周时初始尿意膀胱容量（FVS）、最大尿流率（MFR）、最大尿意膀胱容量（MVS）均较术后1周时升高，残余尿量（PVR）均较术后1周时下降，且研究组术后13周时FVS、MFR、MVS高于对照组，PVR低于对照组（P<0.05）。两组术后13周时血清免疫球蛋白A（IgA）、免疫球蛋白G（IgG）、免疫球蛋白M（IgM）、外周血T淋巴细胞CD3⁺、CD4⁺/CD8⁺均较术后1周时升高，且研究组高于对照组（P<0.05）。研究组尿潴留发生率4.08%（2/49）低于对照组22.45%（11/49），差异有统计学意义（P<0.05）。结论：电针神经刺激疗法联合盆底肌训练可减少早期宫颈癌广泛性全子宫切除术后患者尿潴留的发生率，改善患者的盆底功能和膀胱功能，促进免疫功能恢复，效果较好。

Effects of Electroacupuncture Nerve Stimulation Therapy Combined with Pelvic Floor Muscle Training on Urinary Retention, Bladder Function and Immune Function in Patients with Extensive Total Hysterectomy for Early Cervical Cancer

ABSTRACT Objective: To observe the value of electroacupuncture nerve stimulation therapy combined with pelvic floor muscle training in the rehabilitation of early cervical cancer after extensive total hysterectomy. Methods: 98 patients with early cervical cancer undergoing extensive total hysterectomy who were admitted to our hospital from March 2020 to October 2021 were prospectively collected. They were divided into study group and control group by random number table method. The control group was instructed to conduct pelvic floor muscle training, and the study group was given electroacupuncture nerve stimulation therapy on the basis of pelvic floor muscle training. The incidence of urinary retention and the recovery of bladder function, immune function and pelvic floor function were compared between the two groups. Results: The results of 13 weeks after operation showed that the normal rate of comprehensive muscle strength of pelvic floor muscle in the study group was higher than that in the control group (P<0.05). Initial urinary bladder volume (FVS), maximum urinary flow rate (MFR) and maximum urinary bladder volume (MVS) in two groups at 13 weeks after operation were higher than those at 1 week after operation, while residual urine volume (PVR) was lower than that at 1 week after operation. FVS, MFR and MVS in the study group at 13 weeks after operation were higher than those in the control group, while PVR was lower than that in the control group (P<0.05). The levels of serum immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM), peripheral blood T lymphocyte CD3⁺, CD4⁺/CD8⁺ in the two groups at 13 weeks after operation were higher than those at 1 week after operation, and the study group was higher than the control group (P<0.05). The incidence of urinary retention in the study group was 4.08% (2/49) lower than 22.45% (11/49) in the control group, and the difference was statistically significant (P<0.05). Conclusion: Electroacupuncture nerve stimulation therapy combined with pelvic floor muscle training can reduce the incidence of urinary retention in patients with early cervical cancer after extensive total hysterectomy, improve pelvic floor function and bladder function, and promote the recovery of immune function, and with good effect.