膀胱训练联合生物反馈电刺激改善前列腺癌根治术后患者控尿功能和生活质量的临床研究

摘要 目的：探讨膀胱训练联合生物反馈电刺激改善前列腺癌根治术（RP）后患者控尿功能和生活质量的临床疗效。方法：本研究为前瞻性研究，选取2019年5月~2022年6月期间暨南大学附属第一医院收治的RP术后患者90例，按照随机数字表法分为对照组和研究组，各为45例。在常规干预的基础上，对照组接受膀胱训练，研究组接受膀胱训练联合生物反馈电刺激干预。观察两组临床疗效、尿失禁程度、尿动力学指标和生活质量。结果：研究组的临床总有效率（95.56%）高于对照组（77.78%），组间比较差异有统计学意义（P<0.05）。干预4周后，两组漏尿次数、对日常生活的影响程度、漏尿量、尿失禁问卷表简表（ICI-Q-SF）总分均下降，且研究组低于对照组（P<0.05）。干预4周后，两组最大尿流率（Qmax）、最大膀胱容量（MCC）、最大尿道闭合压（MUCP）和腹压漏尿点压（VLPP）均升高，且研究组高于对照组（P<0.05）。干预4周后，两组尿失禁生活质量问卷（I-QOL）评分均升高，且研究组高于对照组（P<0.05）。结论：膀胱训练联合生物反馈电刺激可有效改善RP术后患者控尿功能，提高临床治疗效果，并有助于生活质量的提升。

Clinical Study on Bladder Training Combined with Biofeedback Electrical Stimulation to Improve Urinary Control Function and Quality of Life in Patients after Radical Prostatectomy

ABSTRACT Objective: To investigate the clinical efficacy of bladder training combined with biofeedback electrical stimulation on urinary control function and quality of life in patients after radical prostatectomy (RP). Methods: This study was a prospective study. 90 patients after RP who were admitted to The First Affiliated Hospital of Jinan University from May 2019 to June 2022 were selected, and they were divided into the control group and the study group according to the random number table, with 45 cases in each group. On the basis of routine intervention, the control group received bladder training, and the study group received bladder training combined with biofeedback electrical stimulation intervention. The clinical efficacy, degree of urinary incontinence, urodynamic index and quality of life in the two groups were observed. Results: The total effective rate in the study group(95.56%) was higher than that in the control group(77.78%), with a statistically significant difference between the groups (P<0.05). 4 weeks after intervention, the number of urine leakage, the degree of influence on quality of life, the volume of urine leakage and the total score of Incontinence Qustionnaire-Short Form (ICI-Q-SF) in the two groups were decreased, and the study group was lower than the control group (P<0.05). 4 weeks after intervention, the maximum urinary flow rate (Qmax), maximum bladder volume (MCC), maximum urethral closure pressure (MUCP) and abdominal pressure leakage point pressure (VLPP) in the two groups were increased, and the study group was higher than the control group (P<0.05). 4 weeks after intervention, the incontinence quality of life instrument (I-QOL) scores in the two groups were increased, and the study group was higher than the control group (P<0.05). Conclusion: Bladder training combined with biofeedback electrical stimulation can effectively improve the urinary control function of patients after RP, improve the clinical treatment effect, and contribute to the improvement of quality of life.