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Novel phantom for performance evaluation of contrast-enhanced 3D rotational angiography
Institution:1. Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok 16424, Indonesia;2. Radiology Department, R. Syamsuddin S.H. Regional General Hospital, Sukabumi 43113, Indonesia;3. Radiology Department, Gading Pluit Hospital, Jakarta 14250, Indonesia;4. Radiotherapy Department, Pasar Minggu Regional General Hospital, Jakarta 12550, Indonesia;5. Medical Physics and Quality Assessment, Catholic University of Leuven, Leuven 3000, Belgium;1. Trillium Health Partners, Peel Regional Cancer Centre, Mississauga, ON, Canada;2. University of Toronto, Department of Radiation Oncology, Toronto, ON, Canada;3. University of Ryerson, Department of Physics, Toronto, Canada;4. Sunnybrook Health Sciences Centre, Toronto, Canada;5. York University, Department of Physics and Astronomy, Toronto, ON, Canada;1. Department of Medical Physics, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku Tokyo 104-0045, Japan;2. Department of Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, 7-2-10, Higashioku, Arakawa-ku Tokyo 116-8551, Japan;3. Division of Research and Development for Boron Neutron Capture Therapy, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, Tsukiji 5-1-1, Chuo-ku, Tokyo 104-0045, Japan;4. Department of Radiation Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku Tokyo 104-0045, Japan;1. AOU Careggi, Medical Physics Unit, Florence, Italy;2. University of Florence-Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, Florence, Italy;3. AOU Careggi, Radiotherapy Unit, Florence, Italy;4. Santa Maria Annunziata Hospital, Radiation Oncology Unit, Florence, Italy;1. Institute of High Energy Physics, Austrian Academy of Sciences, Vienna 1050, Austria;2. Atominstitut, TU Wien, Vienna 1020, Austria;1. Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO. 651 Dongfeng Road, Guangzhou 510060, China;2. Department of Radiotherapy, Zhongshan Affiliated Hospital, Guangzhou University of Chinese Medicine, NO. 3 Kangxin Road West District, Zhongshan 528401, China
Abstract:PurposeThis technical note presents an in-house phantom with a specially designed contrast-object module constructed to address the need for three-dimensional rotational angiography (3DRA) testing.MethodsThe initial part of the study was a brief evaluation on the commercially available phantom used for 3DRA and computed tomography angiography (CTA) to confirm the need for a special phantom for 3D angiography. Once confirmed, an in-house phantom was constructed. The novel phantom was tested to evaluate the basic image performance metrics, i.e., unsharpness (MTF) and noise characterization (NPS), as well as to show its capability for vessel contrast visibility study.ResultsThe low contrast objects in the commercially available tools dedicated for CT is found to yield significantly lower signal difference to noise ratio (SDNR) when used for 3DRA, therefore deemed inadequate for 3DRA contrast evaluation. The constructed in-house phantom demonstrates a capability to serve for basic imaging performance check (MTF, NPS, and low contrast evaluation) for 3DRA and CTA. With higher and potentially adjustable visibility of contrast objects as artificial vessels, the in-house phantom also makes more clinically relevant tests, e.g., human- or model observer study and task-based optimization, possible.ConclusionThe novel phantom with special contrast object module shows higher visibility in 3DRA compared to the currently available commercial phantom and, therefore, is recommended for use in 3D angiography.
Keywords:3D angiography  Imaging performance  Phantom  Quality control
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