Disturbances of mineral metabolism in teeth of rats receiving corticosteroids for 3 generations. |
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| Authors: | R Pawlicki Z Knychalska-Karwin D Stankiewicz K Jakób-Dolezal T Karwan |
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| Institution: | Department of Histology, Institute of Pediatrics, Academy of Medicine, Kraków, Poland. |
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| Abstract: | Distribution of calcium and phosphorus was investigated with quantitative and qualitative methods in teeth of rats chronically treated with low doses of corticosteroids for 3 generations. In animals from 2nd and 3rd generation, scanning electron microscopy revealed focal lesions in enamel and dentin. The disturbances of the mineral metabolism in teeth of corticosteroid-treated rats were also reflected by abnormal calcium and phosphorus content in enamel and dentin, as assessed by X-ray microanalysis. |
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