The effect of F0 inhibitors on the Vibrio alginolyticus membrane ATPase |
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| Authors: | G Capozza O Yu Dmitriev I A Krasnoselskaya S Papa V P Skulachev |
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| Abstract: | The inhibition of membrane ATPase from the marine alkalotolerant bacterium Vibrio alginolyticus by DCCD, triphenyltin and venturicidin was studied. DCCD proved to be an irreversible inhibitor, while venturicidin and triphenyltin produced a reversible inhibitory effect. The DCCD-binding proteolipid was identified in the membrane preparations. The effect of the inhibitors on ATPase activity and ATP-dependent Na+-transport in V. alginolyticus subcellular vesicles is discussed. |
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| Keywords: | Bacterial F0F1-ATPase Na+(H+)-ATPase Vibrio alginolyticus |
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