Isolated interferon alpha-receptor complexes stabilized in vitro |
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Authors: | P Eid K E Mogensen |
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Institution: | Department of Biochemistry, University of Bath, Bath BA2 7AY, England |
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Abstract: | We describe the extraction and stabilization in vitro of discrete complexes of interferon and cellular receptor proteins. A homogeneous complex of Mr 230 000 was extracted at the time of peak receptor binding (30 min). Complex formation was specific for human interferon. At later times a second complex could also be extracted suggesting transfer of interferon to a second site. |
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Keywords: | Citrate synthase Growth dependence Multiple enzyme form |
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