红海葱化学成分和药理作用的研究进展

红海葱(Urginea maritima)是一种可用于治疗多种疾病的常见药用植物,过去临床上常用于治疗咳嗽、水肿、消化不良及肢体疼痛等疾病。现代研究表明,红海葱的主要化学成分为三萜类和黄酮类,具有强心、平喘、抗肿瘤、利尿、祛痰、抗病毒抗菌、抗炎、抗氧化、杀虫等多种药理作用。目前,海葱药理作用研究主要集中在抗肿瘤、抗心衰、平喘方面,然对其具体药效物质基础、作用机制及相应构效关系研究甚少。本文通过查阅国内外与红海葱相关的文献,概述其主要化学成分的结构和药理活性的研究进展,为进一步深入研究红海葱的药效作用机制、提高其利用价值提供参考依据。

Chemical constituents and pharmacological activities of Urginea maritima

Urginea maritima is one of the commonly used botanicals for the treatment of various diseases and has been used clinically to different ailment such as cough,edema,indigestion and pains.Its main chemical components include triterpenoids and flavonoids,which have anti-heart failure,anti-asthma,diuretic,eliminating phlegm and antiasthmatic effects,anti-tumor,anti-viral anti-bacterial,anti-inflammatory antioxidant,insecticide and other biological activities.At present,the pharmacological actions of Urginea maritima mainly focus on anti-heart failure,anti-tumor and anti-asthma.However,there are few studies on the specific pharmacodynamic material basis,mechanism of action and corresponding structure-activity relationship.This paper reviews the main chemical constituents and pharmacological activities of Urginea maritima,and provides a reference for the further development and utilization of Urginea maritima.