| 藏药西藏棱子芹抗炎镇痛药效学研究 |
| |
| 引用本文： | 袁明,李云周,许苗,赵协慧.藏药西藏棱子芹抗炎镇痛药效学研究[J].天然产物研究与开发,2012,24(7):972-975. |
| |
| 作者姓名： | 袁明 李云周 许苗 赵协慧 |
| |
| 作者单位： | 1. 青海大学医学院药学系
2. 青海大学医学院中医系,西宁,810001 |
| |
| 基金项目： | 青海大学国家大学生创新性实验计划项目 |
| |
| 摘 要： | 本文采用二甲苯致小鼠耳廓肿胀法、棉球致小鼠肉芽肿法观察藏药西藏棱子芹的抗炎作用,采用热板法、醋酸扭体法观察藏药西藏棱子芹的镇痛作用。结果表明藏药西藏棱子芹能明显抑制二甲苯所致小鼠耳廓肿胀和棉球所致小鼠肉芽肿;能提高小鼠对热板疼痛的阈值,减少小鼠扭体反应的次数,延长醋酸所致小鼠扭体反应的潜伏时间。藏药西藏棱子芹具有显著的抗炎镇痛作用,值得开发研究。
|
| 关 键 词： | 西藏棱子芹 抗炎 镇痛 药效学 |
Pharmacodynamic Study on Anti-inflammatory and Analgesic Effects of Tibetan Medicine Pleurospermum hookeri var.thomsonii |
| |
| YUAN Ming
,
LI Yun-zhou
,
XU Miao
,
ZHAO Xie-hui.Pharmacodynamic Study on Anti-inflammatory and Analgesic Effects of Tibetan Medicine Pleurospermum hookeri var.thomsonii[J].Natural Product Research and Development,2012,24(7):972-975. |
| |
| Authors: | YUAN Ming LI Yun-zhou XU Miao ZHAO Xie-hui |
| |
| Institution: | 1Department of Pharmacy of Medical College of Qinghai University; 2Department of Traditional Chinese Medicine of Medical College of Qinghai University,Xining 810001,China |
| |
| Abstract: | The anti-inflammatory effects of Tibetan Medicine Pleurospermum hookeri var.thomsonii in mice was observed in test of ear swelling caused by xylene and cotton pellet-induced granuloma mouse method.The analgesic effect of P.hookeri var.thomsonii in mice was observed in hot-plate test and acetic acid-induced writhing.The experiments showed that P.hookeri var.thomsonii could apparently inhibit auricle swelling induced by xylene and cotton pellet-induced granuloma,obviously prolong the pain threshold of temperature stimuli,decrease the number of writhe induced by acetic acid,and reduce the latent twisted body reaction times in mice.Tibetan Medicine P.hookeri var.thomsonii has both anti-inflammatory and analgesic effects obviously,and is worthy of research and development. |
| |
| Keywords: | Pleurospermum hookeri var thomsonii anti-inflammatory analgesic pharmacodynamics |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
