藏药臭蚤草的一个新的苯丙素苷类成分

为了研究藏药臭蚤草的浩性成分，我们利用各种柱色谱技术，从藏药臭蚤草甲醇提取物的乙酸乙酯萃取相分离到4个化合物，通过1D、2DNMR、MS和HRMS等试验，鉴定为2，4-dihydroxy-6-methyl—ethanone-4-O-β-D—Glc（1），4-（3’-hydroxypropyl）-2，6-dimethoxyphenol-3’-O-β-D—glcoside（2），4-allyl-2-methoxyphenol-1-O-β-gleo—side（3），2-methyl-1，3，6-trihydroxy-9，10-anthraquinone-3—O-（6＇-O-Ac）-α—L—Rha-（1→2）-β-D—Gle（4），其中化合物1—3为苯丙素苷类化合物，化合物4为蒽醌苷。化合物1—4都是首次从该属植物中分离得到，化合物1为新的苯丙素苷类化合物。

A New Phenylpropanoid Glycoside from Tibetan Folk Drug Pulicaria insignis

In order to investigate the bioaetivity constituents of Tibetan folk drug Pulicaria insignis, four compounds were isolated with chromatography techniques. Structures were elucidated to be 2,4-dihydroxy-6-methyl-ethanone-4-O-β-D-Glc (1), 45(3 '-hydroxypropyl)-2,6-dimethoxyphenol-3'-O-β-D-gleoside (2), 4-allyl-2-methoxyphenol-1-O-β-D-glcoside (3) , 2-methyl-1,3,6-trihydroxy-9, 10-anthraquinone-3-O-(6'-O-Ac)-α-L-Rha-(1 → 2)-β-D-Gle (4) on the basis of spectroscopic analysis including 1D ,2D-NMR,MS and HRMS. Four compounds were isolated from the genus Pulicaria for the first time. 2,4-Dihydroxy-6-methyl-ethanone-4-O-β-D-Glc(1) is a new phenylpropanoid glycoside.