| 藜叶中黄酮类化合物体外抗氧化活性研究 |
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| 引用本文： | 樊青玲,张耀兮,李天才.藜叶中黄酮类化合物体外抗氧化活性研究[J].天然产物研究与开发,2009,21(4):672-675. |
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| 作者姓名： | 樊青玲 张耀兮 李天才 |
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| 作者单位： | 1. 中国科学院西北高原生物研究所,西宁,810008;中国科学院研究生院,北京,100049
2. 中国科学院西北高原生物研究所,西宁,810008 |
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| 摘 要： | 为了探讨藜叶中黄酮类化合物的体外抗氧化活性，采用有机溶剂提取法和色谱柱法对藜叶中化学成分进行提取与分离；以Vc作对照，对分离纯化的芦丁、乙酸乙酯浸膏和正丁醇浸膏进行DPPH·、O2^-·和·OH的清除效果试验。结果表明：三者对DPPH·、O2^-·、·OH均具有清除作用，且与浓度呈量效关系，芦丁对·OH清除效果优于Vc，芦丁具有较强的清除DPPH·能力，其IC50为0．05μg／mL。
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| 关 键 词： | 藜叶 黄酮类化合物 抗氧化活性 |
Study on Antioxidant Activity in vitro of Flavonoids from Chenopodium album L. Leaves |
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| FAN Qing-ling,ZHANG Yao-xi,LI Tian-cai.Study on Antioxidant Activity in vitro of Flavonoids from Chenopodium album L. Leaves[J].Natural Product Research and Development,2009,21(4):672-675. |
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| Authors: | FAN Qing-ling ZHANG Yao-xi LI Tian-cai |
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| Abstract: | In order to discuss antioxidant activity in vitro of flavonoids from Chenopodium album L. leaves, with solvent extraction method and chromatogram column method, rutin is acquired from Chenopodium album L. leaves; The free radi-cal scavenging activities of rutin,ethyl acetate part and n-butanol part was studied in superoxide anion(O_2~-·) ,hydroxyl radical(·OH) and DPPH · systems ,which is compared with Vc. The results showed the three samples have scavenging capability against DPPH ·, O_2~-·and ·OH radicals in a dose dependent manner, rutin is stronger than V_C for scaven-ging · OH radical, rutin has prominent effect of scavenging DPPH ·radical, IC_(50) is 0.05μg/mL. |
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| Keywords: | Chenopodium album L leaves flavonoids antioxidant activity |
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