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棉花根醇提物与水提物的止咳祛痰抗炎作用研究
引用本文:包淑云,喻丽珍,于禧龙,李永康.棉花根醇提物与水提物的止咳祛痰抗炎作用研究[J].天然产物研究与开发,2011,23(4):730-733.
作者姓名:包淑云  喻丽珍  于禧龙  李永康
作者单位:皖南医学院药学系,芜湖,241002
基金项目:安徽省教育厅自然科学基金一般项目,皖南医学院中青年科研基金
摘    要:制备棉花根醇提物和水提物,止咳实验采用小鼠浓氨水引咳法,祛痰实验采用气管酚红排泌法,抗炎实验采用二甲苯致耳肿胀法,观察棉花根醇提物和水提物的止咳祛痰抗炎作用。实验小鼠分正常对照组,醇提物与水提物高低剂量组及阳性药物对照组。结果发现棉花根醇提物、水提物均能延长小鼠的咳嗽潜伏期,减少咳嗽次数,均能增加气管内的酚红排泌量,对二甲苯所致的耳肿胀均有显著的抑制作用。

关 键 词:棉花根  醇提物  水提物  止咳  祛痰  抗炎

Antitussive, Expectorant and Anti-inflammatory Effects of Ethanol Extract and Water Extract from Cotton Root
BAO Shu-yun,YU Li-zhen,YU Xi-long,LIYong-kang.Antitussive, Expectorant and Anti-inflammatory Effects of Ethanol Extract and Water Extract from Cotton Root[J].Natural Product Research and Development,2011,23(4):730-733.
Authors:BAO Shu-yun  YU Li-zhen  YU Xi-long  LIYong-kang
Institution:BAO Shu-yun,YU Li-zhen,YU Xi-long,LI Yong-kang Department of Pharmacy,Wannan Medical College,Wuhu 241002,China
Abstract:The antitussive,expectorant and anti-inflammatory effects of ethanol extract and water extract from cotton root were studied in this paper.Relieving cough and facilitating expectoration were observed by strong ammonia solution spray and phenol red execretion methods.The anti-inflammation was studied by ear swelling induced by xylene.Ethanol extract and water extract from cotton root both could significantly decrease cough times,prolong incubation period of cough,increase phenol red output in trachea and inh...
Keywords:cotton root  ethanol extract  water extract  antitussive  expectorant  anti-inflammatory  
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