| 壳聚糖对大肠杆菌的抑制作用规律及抗菌机理初探 |
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| 引用本文： | 杨声,冯小强,王廷璞,苏中兴,粱凯强,李会学.壳聚糖对大肠杆菌的抑制作用规律及抗菌机理初探[J].天然产物研究与开发,2007,19(1):39-43. |
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| 作者姓名： | 杨声 冯小强 王廷璞 苏中兴 粱凯强 李会学 |
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| 作者单位： | 1. 天水师范学院生命科学与化学学院,天水,741001
2. 兰州大学化学化工学院,兰州,730000 |
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| 基金项目： | 天水师范学院校科研和教改项目 |
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| 摘 要： | 考察了不同分子量壳聚糖对大肠杆菌的抑菌性能,利用壳聚糖的席夫碱反应对其氨基加以保护,探讨了壳聚糖对大肠杆菌的抗菌机理。研究结果表明:壳聚糖分子量越小,对大肠杆菌的抗菌作用越明显;壳聚糖对大肠杆菌的抑菌作用与其氨基的质子化有关。
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| 关 键 词： | 壳聚糖 大肠杆菌 抑菌 规律 机理 |
| 文章编号： | 1001-6880（2007）01-0039-05 |
| 收稿时间： | 2006-05-12 |
| 修稿时间： | 2006-08-24 |
Study on the Antibacterial Activity and Meachanism of Chitosan on Escherichia coli |
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| YANG Sheng,FENG Xiao-qiang,WANG Ting-pu,SU Zhong-xin,LIANG Kai-qiang,LI Hui-xue.Study on the Antibacterial Activity and Meachanism of Chitosan on Escherichia coli[J].Natural Product Research and Development,2007,19(1):39-43. |
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| Authors: | YANG Sheng FENG Xiao-qiang WANG Ting-pu SU Zhong-xin LIANG Kai-qiang LI Hui-xue |
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| Institution: | 1. College of Biology and Chemistry, Tianshui Normal Univerity , Tianshui 741001, China; 2. Chemistry and Chemical Engineering College, Lanzhou University, Lanzhou 730000, China |
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| Abstract: | The antibacterial ability of chitosan with different molecular weight on Escherichia coli was studied.The antibacterial mechanism was investigated by protecting amino group with Schiff 's base.The study showed that chitosan with lower molecular weight possessed stronger antibacterial ability against Escherichia coli and the antibacterial activity was related to the protonation of amino groups. |
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| Keywords: | chitosan Escherichia coli antibacterial mechanism |
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