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无梗五加根中苯丙素类化合物的研究
引用本文:于凯,宋洋,路阳,熊志立,李发美.无梗五加根中苯丙素类化合物的研究[J].天然产物研究与开发,2012,24(4):469-472.
作者姓名:于凯  宋洋  路阳  熊志立  李发美
作者单位:沈阳药科大学药学院,沈阳,110016
基金项目:supported by the Education Department of Liaoning Province 2009 Key laboratory of colleges and universities plan scientific research projects(No.2009S101)
摘    要:从无梗五加(Acanthoparax sessiliflorus( Rupr.et Maxim.)Seem.)根70%乙醇提取物的乙酸乙酯层中提取分离得到8个苯丙素类化合物.经理化和波谱分析鉴定为(+)-表芝麻脂素(1)、(-)-芝麻脂素(2)、赛菊芋黄素(3)、洒维宁(4)、咖啡酸甲酯(5)、对羟基桂皮酸(6)、(-)-丁香脂素(7)、(+)-松脂索(8).化合物8是首次从五加科植物中分离得到,化合物1和5是首次从五加属植物中分离得到,化合物3、6和7是首次从该植物中分离得到.

关 键 词:无梗五加根  苯丙索类化合物  (+)-表芝麻脂索  咖啡酸甲酯  (+)-松脂素

Phenylpropanoids from Roots of Acanthopanax sessiliflorus ( Rupr.et Maxim.) Seem.
YU Kai , SONG Yang , LU Yang , XIONG Zhi-li , LI Fa-mei.Phenylpropanoids from Roots of Acanthopanax sessiliflorus ( Rupr.et Maxim.) Seem.[J].Natural Product Research and Development,2012,24(4):469-472.
Authors:YU Kai  SONG Yang  LU Yang  XIONG Zhi-li  LI Fa-mei
Institution:* School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China
Abstract:Eight phenylpropanoids were isolated from the ethyl acetate fraction of the 70% ethanol extract of the roots of Acanthopanax sessiliflorus(Rupr.et Maxim.) Seem..Their structures were elucidated by physicochemical properties and spectroscopic analysis as(+)-episesamin(1),(-)-sesamin(2),helioxanthin(3),savinin(4),caffeic acid methyl ester(5),p-hydroxycinnamic acid(6),(-)-syringaresinol(7),and(+)-medioresinol(8).Compound 8 was isolated from Araliaceae for the first time,compounds 1 and 5 were obtained from Acanthopanax genus for the first time,and compounds 3,6,and 7 were isolated from this plant for the first time.
Keywords:Acanthopanax sessiliflorus (Rupr  et Maxim  ) Seem    phenylpropanoids  ( + )-episesamin  caffeic acid methyl ester  ( + )-medioresinol
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