湖北旋覆花化学成分的研究(英文)

从湖北旋覆花(Inula hupehensis)地上部分分离得到19个化合物,经波谱数据分析分别鉴定为9-羟基-百里香酚(1),8,10-去氢-β-羟基-百里香酚(2),2-羟基-4-甲基苯乙酮(3),8,9-双羟基-9-百里香酚(4),10-羟基-8,9-双氧亚异丙基百里香酚(5),8,10-二羟基-9-异丁酰百里香酚(6),8-羟基-9-异丁酰-10-(2-甲基丁酰)百里香酚(7),8,9,10-三羟基百里香酚(8),8-羟基-9,10-二异丁酰百里香酚(9),neoechinulin A(10),3-醛基吲哚(11),3-羟乙酰基吲哚(12),丁香酸(13),4,6-二羟基-2-甲氧基苯乙酮(14),7-甲氧基-8-羟基香豆素(15),6-甲氧基山奈酚(16),(+)-正丁香酯素(17),β-棕榈精(18)和豆甾醇(19)。除了化合物8和9外,其他化合物均为首次从该植物中分离得到。

Chemical Constituents from Inula hupehensis

Nineteen compounds were isolated from the aerial parts of Inula hupehensis.On the basis of spectral data,their structures were identified as 9-hydroxythymol(1),8,10-dehydro-9-hydroxythymol(2),2-hydroxy-4-methylacetophenone(3),8,9-dihydroxythymol(4),10-hydroxy-8,9-dioxyisopropylidenethymol(5),8,10-dihydroxy-9-isobutyryloxythymol(6),8-hydroxy-9-(isobutyryl)oxy]-10-(2-methylbutanoyl)thymol(7),8,9,10-trihydroxythymol(8),8-hydroxy-9,10-diisobutyryloxythymol(9),neoechinulin A(10),3-formyl-indole(11),3-(hydroxyl-acetyl)-1H-indole(12),syringic acid(13),4,6-dihydroxy-2-methoxyacetophenone(14),daphnetin 7-methyl ether(15),6-methoxykaemaferol(16),(+)-syringaresinol(17),α-monopalmitin(18),and stigmasterol(19).All the compounds except compounds 8 and 9 were isolated from this plant for the first time.