抗菌肽CM4对串珠镰孢菌孢子的抑制杀伤效应

The fungicidal effect of the antibacterial peptide CM4 from Chinese silkworm on Fusaricum moniliforme]

The antibacterial peptide CM4 inhibits growth of conidia of Fusaricum moniliforme. The observation by using the electron microscope showed that some cells were empty and interior structure twisted into helix. Conidia cells in control group were in good condition, normally grew up. The fungal conidia treated with the antibacterial peptide CM4, then confocal laser scanning microscope were performed. As a result, it was showed that FITC-labeled peptide assembled in cells, centre of which had more peptides than two ends. Then conidia split, became empty. Finally the cells plasma membrane disintegrated and died, lead to small fragments.