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化脓性中耳炎病原菌感染的研究进展
引用本文:刘瑞杰,王鑫霞,王露,赵梓尧,余驰昊,俞洪,杨雪静,孙桂芹.化脓性中耳炎病原菌感染的研究进展[J].微生物与感染,2020,15(2):129-134.
作者姓名:刘瑞杰  王鑫霞  王露  赵梓尧  余驰昊  俞洪  杨雪静  孙桂芹
作者单位:1. 浙江中医药大学医学技术学院,杭州 310053; 2. 浙江中医药大学基础医学院,杭州 310053; 3. 浙江中医药大学附属第一医院检验科,杭州 310006
基金项目:国家自然科学基金(31600644), 浙江中医药大学校级科研基金(2019ZY23)
摘    要:化脓性中耳炎是耳鼻喉科临床常见疾病,可导致听力下降、鼓膜充血、鼓膜穿孔、耳鸣、耳痛及流脓等。化脓性中耳炎主要由微生物进入中耳引起感染,使中耳黏膜发生化脓性病变,且不同患者感染的病原菌不同。本文从化脓性中耳炎的发病机制、病原菌及其耐药性和治疗方法等几个方面进行综述,以期为临床化脓性中耳炎的诊断及合理用药提供参考。

关 键 词:化脓性中耳炎  感染  病原菌  检测  耐药  治疗  

Advances in suppurative otitis media caused by pathogenic infections
LIU Ruijie,WANG Xinxia,WANG Lu,ZHAO Ziyao,YU Chihao,YU Hong,YANG Xuejing,SUN Guiqin.Advances in suppurative otitis media caused by pathogenic infections[J].Journal of Microbes and Infection,2020,15(2):129-134.
Authors:LIU Ruijie  WANG Xinxia  WANG Lu  ZHAO Ziyao  YU Chihao  YU Hong  YANG Xuejing  SUN Guiqin
Institution:1. College of Medical Technology, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China; 2. School of Basic Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China; 3. Department of Clinical Laboratory, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang Province, China
Abstract:Suppurative otitis media is a common disease in the department of otolaryngology, which would result in hearing loss, tympanic membrane congestion, tympanic membrane perforation, tinnitus, ear pain and purulent clinical symptoms. Suppurative otitis media is mainly associated with microorganisms that could cause the middle ear infection and the middle ear suppurative lesions. In this paper, the pathogenesis of suppurative otitis media, pathogenic bacteria, drug resistance and treatment methods were summarized to provide evidence for clinical diagnosis and rational drug use of suppurative otitis media.
Keywords:Suppurative otitis media  Infection  Pathogenic bacteria  Detection  Drug resistance  Treatment  
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