羧酸酯酶和乙酰胆碱酯酶在褐飞虱对马拉硫磷抗性发展中的作用

对室内筛选褐飞虱Nilaparvata lugens Stal对马拉硫磷抗性及羧酸酯酶、乙酰胆碱酯酶的连续变化进行了研究。结果表明，抗性发展在不同世代之间存在一定的变化。LD₅₀的最大变化发生在第3代和第5代之间。在筛选的前5代，羧酸酯酶活性上升与马拉硫磷抗性变化存在很好的相关性，而乙酰胆碱酯酶敏感性在第6代和第8代间的变化与抗性发展存在很好的相关性。可见，羧酸酯酶活性的上升在抗性发展的早期阶段起重要作用，而乙酰胆碱酯酶不敏感在抗性发展的后期阶段起更重要作用。

The roles of carboxylesterase and AChE insensitivity in malathion resistance development in brown planthopper

Malathion resistance of brown planthopper (Nilaparvata lugens Stal) was selected in laboratory and the successive changes in carboxy-lesterase (CarE) and AChE were also analyzed. The results showed that the speed of resistance selection varied with generations. The biggestchange of LD50 occurred between the 3rd - 5th generations. The rise of carboxylesterase activity was correlated with the change in malathion resis-tance for the first 5 generations, while change in AChE sensitivity between 6th- 8th generations had a higher correlation with the resistance devel-opment. Therefore, it was concluded that carboxylesterase activity increase play important role in the early stage of the resistance development andthe AChE insensitivity at the late stage.