有机磷药剂对棉铃虫羧酸酯酶的抑制作用

该文分别以。A-乙酸萘酯和β-乙酸萘酯为底物比较了22种常用有机磷药剂对棉铃虫 Helicoverpa armigera羧酸酯酶的抑制作用。结果表明，棉铃虫羧酸酯酶对底物空间构型比较敏感，敌敌畏、对氧磷、地亚农、喹硫磷、马拉氧磷、异稻瘟净、增效磷、杀螟松抑制棉铃虫羧酸酯酶的能力较强。有机磷药剂抑制棉铃虫羧酸酯酶能力与其化学结构显著相关，氧化型的有机磷抑制能力明显强于硫代型的有机磷；乙氧基取代的有机磷抑制能力明显强于甲氧基取代的有机磷。

INHIBITION OF ORGANOPHOSPHATE INSECTICIDES TOCARBOXYLESTERASE IN HELICO VERPA ARMIGERA

The inhibition of 22 organophosphates (OP) to the activity of carboxylesterase, usinga-and β-naphthyl acetate as substrate separately, was investigated in cotton bollworms ( Helicoverpaarmigera ). The inhibition potential of paraoxon, dichlorvos, SV1, quinalphos, malaoxon, IBP were much stronger than the other insecticides tested. The relationship between chemical structureand the inhibition potential to carboxylesterase was also studied. The inhibition potential was: phosphate > phosphorothionate, phosphorothiolate > phosphorodithioate, phosphoramidate > phosphorothiolamidate and (C2H5O)2OP > (CH3O)2OP.