Reduction of severe acute respiratory syndrome coronavirus-2 infectivity by admissible concentration of ozone gas and water |
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| Authors: | Takayuki Murata Satoshi Komoto Satoko Iwahori Jun Sasaki Hironori Nishitsuji Terumitsu Hasebe Kiyotaka Hoshinaga Yukio Yuzawa |
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| Institution: | 1. Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Japan;2. Department of Radiology, Tokai University Hachioji Hospital, Tokai University School of Medicine, Hachioji, Tokyo, Japan;3. Department of Urology, Fujita Health University School of Medicine, Toyoake, Japan;4. Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Japan |
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| Abstract: | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the global coronavirus disease 2019 (COVID-19) pandemic. Because complete elimination of SARS-CoV-2 appears difficult, decreasing the risk of transmission is important. Treatment with 0.1 and 0.05 ppm ozone gas for 10 and 20 hr, respectively, decreased SARS-CoV-2 infectivity by about 95%. The magnitude of the effect was dependent on humidity. Treatment with 1 and 2 mg/L ozone water for 10 s reduced SARS-CoV-2 infectivity by about 2 and 3 logs, respectively. Our results suggest that low-dose ozone, in the form of gas and water, is effective against SARS-CoV-2. |
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| Keywords: | humidity ozone gas ozone water SARS-CoV-2 TCID50 |
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