Chemical composition and antimicrobial activity of the essential oil of Teucrium ramosissimum (Lamiaceae) |
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Authors: | Ben Sghaier Mohamed Chraief Imed Skandrani Ines Bouhlel Ines Boubaker Jihed Kilani Soumaya Neffati Aïcha Mahmoud Amor Hammami Mohamed Chekir-Ghedira Leila Ghedira Kamel |
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Institution: | Unity of Pharmacognosy/Molecular Biology 99/UR/07-03, Faculty of Pharmacy, Rue Avicenne, Monastir, 5000, Tunisia. |
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Abstract: | The phytochemical composition of the essential oil of Teucrium ramosissimum (aerial parts), harvested in a mountainous region of Tunisia, was analyzed. A total of 68 compounds, accounting for 99.44% of the essential oil, were identified by GC and GC/MS. The major compounds were beta-eudesmol (61; 44.52%), caryophyllene oxide (56; 9.35%), alpha-thujene (1; 5.51%), sabinene (4; 4.71%), and T-cadinol (59; 3.9%). The essential oil, which is being used in Tunisian folk medicine against infectious diseases, was tested for its antimicrobial properties against five different bacteria, and found to have weak to moderate activity, with minimal-inhibitory-concentration (MIC) and minimal-bactericidal-concentration (MBC) values in the range 0.24-0.36 and 1.3-2.9 mg/ml, resp. |
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Keywords: | Teucrium ramosissimum Antimicrobial activity Essential oils |
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