(1) Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA;(2) Dept. of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA
Abstract:
Background
Algorithmic approaches to splice site prediction have relied mainly on the consensus patterns found at the boundaries between protein coding and non-coding regions. However exonic splicing enhancers have been shown to enhance the utilization of nearby splice sites.