Measurement of (5′R)- and (5′S)-8,5′-cyclo-2′-deoxyadenosines in DNA in vivo by liquid chromatography/isotope-dilution tandem mass spectrometry期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

*Measurement of (5′R)- and (5′S)-8,5′-cyclo-2′-deoxyadenosines in DNA in vivo* by liquid chromatography/isotope-dilution tandem mass spectrometry**

Authors:	Pawel Jaruga Yan Xiao Miral Dizdaroglu

Affiliation:	^a Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA ^b Department of Clinical Biochemistry, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland

Abstract:

Keywords:	BER, base excision repair R-cdA, (5&prime R)-8,5&prime -cyclo-2&prime -deoxyadenosine S-cdA, (5&prime S)-8,5&prime -cyclo-2&prime -deoxyadenosine GC/MS, gas chromatography/mass spectrometry 0" alt=" radical dot" src=" http://cdn.els-cdn.com/sd/entities/rad" class=" glyphImg" >OH, hydroxyl radical 8-OH-dG, 8-hydroxy-2&prime -deoxyguanosine 8-OH-dA, 8-hydroxy-2&prime -deoxyadenosine LC/MS, liquid chromatography/single stage mass spectrometry LC/MS/MS, liquid chromatography/tandem mass spectrometry NER, nucleotide excision repair LOD, limit of detection LOQ, limit of quantification S/N, signal-to-noise ratio SRM, selected-reaction monitoring
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