Glutamic acid decarboxylase (GAD)-like immunoreactivity in the pedal ganglion of Mytilus galloprovincialis |
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Authors: | Dr S De Biasi C Frassoni L Vitellaro Zuccarello |
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Institution: | (1) Dipartimento di Fisiologia e Biochimica Generali, Sezione di Istologia ed Anatomia Umana, Università di Milano, Italy;(2) Istituto Neurologico CBesta, Milano, Italy;(3) Dipartimento di Fisiologia e Biochimica Generali, Sezione di Istologia ed Anatomia Umana, Via Celoria 26, I-20133 Milano, Italy |
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Abstract: | Summary A substance immunologically related to vertebrate glutamic acid decarboxylase (GAD) has been visualized in the pedal ganglion of Mytilus with the pre-embedding peroxidase-antiperoxidase method, by use of an antiserum raised in sheep against rat brain GAD. The results show that GAD-like immunoreactivity is present both in neuronal perikarya and in nerve fibers. Positive neurons are located mainly among the fibers of the ganglion neuropil at the commissural level, and more rarely close to unreactive cortical cell bodies. Immunoreactive nerve fibers are observed throughout the neuropil and also in cerebropedal and pedal nerves.Supported by Ministero Pubblica Istruzione (40%) |
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Keywords: | Immunocytochemistry GAD Pedal ganglion Invertebrate nervous system Mytilus galloprovincialis |
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