Study of the urine proteome in healthy humans |
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| Authors: | I. V. Dobrokhotov L. Kh. Pastushkova I. M. Larina E. N. Nikolaev |
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| Affiliation: | 1.Institute of Biomedical Problems,Russian Academy of Sciences,Moscow,Russia;2.Emanuel Institute of Biochemical Physics,Russian Academy of Sciences,Moscow,Russia |
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| Abstract: | A new branch of molecular biology, proteomics, has been developed recently due to a success in genomics and informatics. Proteomics is currently solving problems of the full proteome mapping of various biological substances, e.g., body fluids, cells, and tissues in the normal state and pathology; and also search for biomarkers of pathologies, including tumors. Data on the urine proteome have been analyzed in this review. Analysis of the methods used in proteomics, including sample preparation, study strategy, as well as published data on urine proteome over the past five years are presented. |
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