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Fluctuations in human serum lipoproteins during the normal menstrual cycle |
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| Authors: | Marion Barclay R K Barclay V P Skipski Olga Terebus-Kekish C H Mueller Ellen Shah and W L Elkins |
| Institution: | Division of Experimental Chemotherapy, Sloan–Kettering Institute for Cancer Research, Rye, N.Y., and Sloan–Kettering Division, Graduate School of Medical Sciences, Cornell University Medical College, New York 21, N.Y., U.S.A. |
| Abstract: | 1. Lipoproteins were measured in sera from 11 young women having a similar environment and diet. Sera were obtained at weekly intervals over a 12-week period. The values of the lipoproteins during periods in the normal ovulatory cycle were compared to assess their relation to reported hormone concentrations in blood. 2. Only the 4–0sf (HDL2) (d 1·125 sodium chloride) fraction changed significantly; it increased at ovulation in ten of the 11 subjects and fell as menstruation approached. 3. There was greater variability in most of the low-density rather than the high-density lipoproteins within individuals. The lipoprotein class most characteristic for an individual was the 4–0sf or HDL2 fraction. |
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