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Determination of multielement concentrations in normal human organs from the Japanese
Authors:Katoh Yoh  Sato Takeo  Yamamoto Yoshio
Affiliation:(1) Faculty of Health Sciences, Tokyo Metropolitan University of Health Sciences, Tokyo, Japan;(2) Tokyo Metropolitan Institute Neuroscience, Shiga University of Medical Science, Shiga, Japan;(3) Department of Legal Medicine, Shiga University of Medical Science, Shiga, Japan
Abstract:In order to elucidate the distribution of elements in organs from healthy Japanese, instrumental neutron activation analysis (INAA), based on the preliminary examination, was applied to quantitative determination of multielements in nine organs autopsied (brain, heart, kidney, liver, lung, muscle, pancreas, spleen, and thyroid). The following results were obtained: (1) The values obtained for each element could be considered to be representative as "normal values" and "ranges" in organs from healthy Japanese males; (2) the essential elements Br, Cl, Co, Cu, Fe, K, Mn, Na, Rb, Se, and Zn were not affected by external environmental factors or by racial difference; (3) renal and hepatic Cd levels were very high in several cases and the accumulation has still been in progress in the Japanese, whereas the contaminant elements are low in each organ except for lung.
Keywords:Neutron activation analysis  multielement  human organs  normal values  Japanese
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