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New Metabolites from Endolichenic Fungus Pleosporales sp.
Authors:Yang Jiao  Gang Li  Hai‐Ying Wang  Jing Liu  Xiao‐Bin Li  Lu‐Lu Zhang  Zun‐Tian Zhao  Hong‐Xiang Lou
Institution:1. Department of Natural Products Chemistry, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Shandong University, No.?44 West Wenhua Road, Jinan 250012, P.?R. China, (phone: +86‐531‐88382012;2. fax: +86‐531‐88382019);3. College of Life Sciences, Shandong Normal University, No.?88 East Wenhua Road, Jinan 250014, P.?R. China (phone: +86‐531‐86180719;4. fax: +86‐531‐86180749)
Abstract:Eight new metabolites were obtained from the culture of an endolichenic fungus, Pleosporales sp. Their structures were determined as three terphenyl derivatives, cucurbitarins A–C ( 1 – 3 , resp.), two structurally related compounds, cucurbitarins D and E ( 4 and 5 , resp.), two benzocoumarins, 3,10‐dihydroxy‐4,8‐dimethoxy‐6‐methylbenzocoumarin ( 6 ) and 3,8,10‐trihydroxy‐4‐methoxy‐6‐methylbenzocoumarin ( 7 ), as well as one cyclohexenone, (5R)‐5‐hydroxy‐2,3‐dimethylcyclohex‐2‐en‐1‐one ( 8 ), based on the spectroscopic data.
Keywords:Benzocoumarins  Cucurbitarins  Fungi  Endolichenic fungi  Pleosporales  Terphenyl derivatives
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