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4α‐Acetoxyamijidictyol – A New Antifeeding Dolastane Diterpene from the Brazilian Brown Alga Canistrocarpus cervicornis |
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| Authors: | Éverson Miguel?Bianco Thiago Martins?Francisco Carlos Basílio?Pinheiro Rodrigo Bagueira?de?Vasconcellos?Azeredo Valéria Laneuville?Teixeira Renato Crespo?Pereira |
| Institution: | 1. Programa de Pós‐gradua??o em Química, Departamento de Química, Funda??o Universidade Regional de Blumenau, Campus 1, Bloco S, Victor Konder, CEP 89012‐900, Blumenau, SC, Brazil, (phone: +55‐47‐33210615);2. Programa de Pós‐gradua??o em Química Organica, Instituto de Química, Universidade Federal Fluminense, Outeiro de S?o Jo?o Baptista, Campus do Valonguinho, s/n, CEP 24020‐150, Niterói, RJ, Brazil;3. Departamento de Física, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Campus da Pampulha, P.?O. Box 702, 30123‐970, Belo Horizonte, MG, Brazil;4. Departamento de Biologia Marinha, Instituto de Biologia, Outeiro de S?o Jo?o Baptista, Campus do Valonguinho, s/n, P.?O. Box 100.644, CEP 24001‐970, Niterói, RJ, Brazil |
| Abstract: | Chemical investigation of the CH2Cl2 crude extract from the brown alga Canistrocarpus cervicornis (Dictyotaceae) led to isolation of one new ( 1 ) and four previously reported dolastane diterpenes ( 2 – 5 ). Their structures were characterized by 1D‐ and 2D‐NMR spectroscopic techniques, including a full single crystal X‐ray diffraction analysis for 1, 2 , and 4 . In addition, the new structure 1 was assayed as chemical defense inhibiting the feeding by the sea urchin Lytechinus variegatus. This study constitutes an additional report broadening the known spectrum of action and defensive roles of secondary metabolites of the C. cervicornis and Dictyotales species. |
| Keywords: | Canistrocarpus cervicornis Dolastane diterpene Antifeeding 4α ‐Acetoxyamijidictyol |