Substituted 1,6-naphthyridines as human cytomegalovirus inhibitors: conformational requirements |
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Authors: | Falardeau G Chan L Stefanac T May S Jin H Lavallée J F |
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Affiliation: | BioChem Pharma Inc., 275 Armand-Frappier Blvd., Laval, Québec, Canada H7V 4A7 |
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Abstract: | ![]() Substituted 1,6-naphthyridine derivatives, a new class of human cytomegalovirus inhibitors, were prepared to demonstrate the role of intramolecular hydrogen bonds to maintain the compounds in their active conformation. |
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