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Substituted 1,6-naphthyridines as human cytomegalovirus inhibitors: conformational requirements
Authors:Falardeau G  Chan L  Stefanac T  May S  Jin H  Lavallée J F
Affiliation:

BioChem Pharma Inc., 275 Armand-Frappier Blvd., Laval, Québec, Canada H7V 4A7

Abstract:
Substituted 1,6-naphthyridine derivatives, a new class of human cytomegalovirus inhibitors, were prepared to demonstrate the role of intramolecular hydrogen bonds to maintain the compounds in their active conformation.
Keywords:
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