Active muscle fiber as an equivalent cardiac current generator |
| |
Authors: | L Munk E P George |
| |
Institution: | (1) School of Physics, University of New South Wales, New South Wales, Australia |
| |
Abstract: | Equations are derived describing potentials due to an active muscle fiber in an infinite medium in terms of two surface integrals—one
of the propagated action potential and the other of the membrane current density, both integrals being taken over the surface
of the muscle.
These equations are incorporated into an equivalent cardiac current generator in which the left ventricle (i.e. the current
source) is represented by a three-dimensional wedge and the thorax (i.e. the volume conductor), by a homogeneous circular
cylinder. Since this current generator expresses the body surface potentials in terms of the membrane current density and
the membrane potential at any point on the surface of the electrically active muscle fiber, the calculated ECG can be correlated
with theactual sources within the heart. This equivalent cardiac generator possesses many of the physical and physiological properties of
cardiac muscle.
The equations were evaluated numerically on a digital computer. The results indicate that equivalent cardiac current generators
of this type can yield clinically significant results and that further research is necessary to investigate their properties
fully. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|