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Dynamic expression of Dab2 in the mouse embryonic central nervous system
Authors:Kwok-Kuen Cheung  Samuel C Mok  Payam Rezaie  Wood Yee Chan
Institution:(1) Department of Anatomy, Faculty of Medicine, The Chinese University of Hong Kong, PR, China;(2) Department of Rehabilitation Sciences, The Hong Kong Polytechnic, University, Hung Hom, Hong Kong, PR, China;(3) Department of Gynecologic Oncology University of Texas M.D., Anderson Cancer Center T4.3908, 1515 Holcombe Boulevard Houston, 77030, TX, USA;(4) Neuropathology Research Laboratory, Department of Life Sciences, Faculty of Science, The Open University, Walton Hall, MK7 6AA Milton Keynes, UK;(5) Department of Neuroscience, Institute of Psychiatry, King's College London, DeCrespigny Park, SE5 8AF London, UK
Abstract:

Background  

Dab2, one of two mammalian orthologs of Drosophila Disabled, has been shown to be involved in cell positioning and formation of visceral endoderm during mouse embryogenesis, but its role in neuronal development is not yet fully understood. In this report, we have examined the localization of the Dab2 protein in the mouse embryonic central nervous system (CNS) at different developmental stages.
Keywords:
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