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Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice
Authors:David J. Cantor  Bryan King  Lili Blumenberg  Teresa DiMauro  Iannis Aifantis  Sergei B. Koralov  Jane A. Skok  Gregory David
Affiliation:1. Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA;2. Department of Pathology, New York University School of Medicine, New York, NY 10016, USA;3. Department of Urology, New York University School of Medicine, New York, NY 10016, USA;4. Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA
Abstract:
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  • Keywords:B cell development  B lymphocytes  BMI1  polycomb  VDJ recombination  immunoglobulin  heavy chain  pre-B cell proliferation  p53 signaling
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