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Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections
Authors:Larissa B. Thackray  Scott A. Handley  Matthew J. Gorman  Subhajit Poddar  Prachi Bagadia  Carlos G. Briseño  Derek J. Theisen  Qing Tan  Barry L. Hykes  Hueylie Lin  Tiffany M. Lucas  Chandni Desai  Jeffrey I. Gordon  Kenneth M. Murphy  Herbert W. Virgin  Michael S. Diamond
Affiliation:1. Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA;2. Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA;3. Center for Genome Sciences and Systems Biology, Washington University School of Medicine, Saint Louis, MO 63110, USA;4. Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, Saint Louis, MO 63110, USA;5. Howard Hughes Medical Institute, Washington University School of Medicine, Saint Louis, MO 63110, USA;6. Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA;7. The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA
Abstract:
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  • Keywords:West Nile virus  Dengue virus  Zika virus  flavivirus  oral antibiotics  gut microbiota  risk factors  pathogenesis determinants  immunity
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