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TBX18 transcription factor overexpression in human-induced pluripotent stem cells increases their differentiation into pacemaker-like cells
Authors:Armita M. Gorabi  Saeideh Hajighasemi  Hossein A. Tafti  Amir Atashi  Masoud Soleimani  Nasser Aghdami  Ali K. Saeid  Vahid Khori  Yunes Panahi  Amirhossein Sahebkar
Affiliation:1. Department of Basic and Clinical Research, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran;2. Department of Medical Biotechnology, Faculty of Paramedicine, Qazvin University of Medical Sciences, Qazvin, Iran;3. Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran;4. Stem Cell and Tissue Engineering Research Center, Shahroud University of Medical Sciences, Shahroud, Iran;5. Department of Hematology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran;6. Department of Regenerative Biomedicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran;7. Department of Cardiology, Tehran University of Medical Science, Tehran, Iran;8. Ischemic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran;9. Pharmacotherapy Department, School of Pharmacy, Baqiyatallah University of Medical Sciences, Tehran, Iran;10. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:
Keywords:cardiomyocyte (CM)  human-induced pluripotent stem cell (hiPSC)  pacemaker-like cells  sinoatrial node (SAN)  T-box 18 (TBX18)  transduction
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