妊娠合并甲状腺功能减退症26例妊娠结局分析

目的：对妊娠合并甲状腺功能减退症进行分析,探讨其对母儿的影响,及孕期筛查甲状腺功能有无意义。方法：对我院26例妊娠合并甲减的临床资料进行回顾性统计分析。结果：26例妊娠合并甲减病例中有1例早产（孕33周）,其余25例患者维持至足月妊娠,其中剖宫产17例（65.38%）,合并妊娠期高血压疾病5例（19.23%）,妊娠期糖尿病3例（11.53%）,羊水胎粪污染3例（11.54%）,新生儿无先天性甲减。经过治疗后甲状腺功能减退孕妇的剖宫产率,糖尿病发生率、高血压疾病发生率、羊水粪染的发生率较对照组增加;但两组妊娠结局差异无统计学意义（P〉0.05）。结论：妊娠合并甲状腺功能减退症孕妇多种妊娠并发症的发病率高于正常孕妇,应加强对妊娠甲减的早期筛查及治疗,可有效降低不良妊娠结局,减少先天性甲低的出生。

Outcome of 26 Pregnant Women with Hypothroidism

Objective： To analyze the maternal and fetal outcome of pregnant women combined with treated hypothroidism, and analyze the value of early screening of thyroid ruction. Methods： Data of 26 cases of pregnant women with hypothyroidism were analyzed retrospectively. Results： In 26 cases of pregnant women with hypothyroidism, 1 was preterm labor, 25 full-term pregnancy, 17 uterine lower segment cesarean section （65.38%）, 5 hypertensive disorders complicating pregnancy （19.23%）, 3 gestational diabetes mellitus （11.53%）, 3 meconium-stained amniotic fluid （11.54%）, no congenital hypothyroidism. The patients in hypothyroidism group had a higher risk of cesarean-section, gestational diabetes mellitus, gestational hypertension and meconium-contaminated amniotic fluid but there was no statistical difference between hypothyroidism and control group （P〉0.05）. Conclusion： The incidence of the pregnancy complication with hypothy- roidism increased than normal pregnancy women. Early sceening and proper treatment for the pregnant women with hypothyroidism can effectively reduce the adverse pregnancy outcome, and the birth of congenital hypothyroidism.