Development and set-up of a portable device to monitor airway exhalation and deposition of particulate matter |
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Authors: | Matteo Goldoni Andrea Caglieri Giuseppe De Palma Sonia Longo Olga Acampa Diana Poli |
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Affiliation: | 1. Department of Experimental and Applied Medicine, Section of Industrial Hygiene, University of Brescia, Brescia, Italy;2. Laboratory of Industrial Toxicology, Department of Clinical Medicine, Nephrology and Health Sciences, University of Parma, Parma, Italy |
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Abstract: | The aim of this study was to assess and monitor airway exhalation and deposition of particulate matter (PM). After standardizing inspiratory/expiratory flow and volumes, a novel device was tested on a group of 20 volunteers and in a field study on workers exposed to cristobalite. Both male and female subjects showed a higher percentage of deposition in the 0.5?μm channel than in the 0.3?μm channel on a laser particle counter, but it was higher in the males because of their higher exhaled lung volumes. The device was tested on a wider range of particles (0.3–0.5–1.0–2.5?μm) in the cristobalite productive division. The device has low intrasubject variability and good reproducibility, with geometric mean of %CV?5%. Such a measure can be used to assess individual susceptibility to PM, making repeated measures in different environments, and examining the persistence of particles in the airways after a period in polluted environments. |
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Keywords: | Particulate matter airway deposition particle exhalation susceptibility vital capacity |
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