Lignans, an amide and anti-platelet activities from Piper philippinum |
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Authors: | Chen Yu-Chang Liao Chang-Hui Chen Ih-Sheng |
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Affiliation: | Graduate Institute of Pharmaceutical Sciences, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan, ROC. |
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Abstract: | Investigation of the stem extract of Piper philippinum led to isolation of eight compounds, piperphilippinins I-VI (1-6), philippinamide (7), and (+)-bornyl caffeate (8), together with 26 known compounds. Among the isolates, (-)-3',4'-O,O-demethylenehinokinin (10) and 3,4-methylenedioxycinnamaldehyde (23) showed anti-platelet activities in vitro. |
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