Static input-output relations in the spinal recurrent inhibitory pathway |
| |
Authors: | S Cleveland A Kuschmierz H-G Ross |
| |
Institution: | (1) Physiologisches Institut (Lehrstuhl II), Universität Düsseldorf, D-4000 Düsseldorf, Federal Republic of Germany |
| |
Abstract: | The static discharge rate of Renshaw cells (studied in deafferented, intercollicularly decerebrate cats) has a nonlinear dependence on the frequency of trains of stimulus impulses to -motor axons in the ventral root. This dependence is well described by a rectangular hyperbola that approaches saturation with increasing stimulus frequency. The tendency to saturate is independent of the number of motor axons exciting a Renshaw cell. On average, the stimulus frequency at which the discharge rate reaches half its saturation value lies between 10 and 15 Hz. The effect of Renshaw cell activity — measured as the antidromic inhibition of individual -motoneurons — reflects the form of the static frequency characteristics. An electric circuit analog of the Renshaw cell membrane is presented which serves to explain the qualitative features of the static input-output relations; the nonlinearity is the result of synapses with linear properties acting together at the cell membrane.Dedicated to Professor R. Granit, Stockholm, on the occasion of his 80th birthday |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|