Long-chain omega 3 fatty acids: Molecular bases of potential antioxidant actions |
| |
| Affiliation: | 1. Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic;2. Human and Animal Physiology, Wageningen University, Wageningen, Netherlands;3. 4th Department of Internal Medicine, 1st Faculty of Medicine of Charles University and the General Teaching Hospital, Prague, Czech Republic;1. Geriatric Research, Education and Clinical Center, Veterans Affairs Pittsburgh Health Care System, Pittsburgh, PA 15261, USA;2. Pittsburgh Institute of Brain Disorders & Recovery and Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA;3. Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan;1. Fats and Oils Department, National Research Centre, Egypt;2. Chemistry Department, Faculty of Science, Ain Shams University, Egypt;3. Agricultural Research Center – Plant Pathology Research Institute, 9 Gamaa St., 12619 Giza, Egypt;4. Department of Physical Chemistry, Wroclaw Medical University, Poland;5. Center of Materials Science (CMS), Zewail City of Science and Technology, Egypt |
| |
| Abstract: | Several lines of investigation are being developed to assess the impact of polyunsaturated fatty acids, namely those of the omega 3 series, intake on oxidative stress. Keeping in mind that there might be a dose-response relation, in vivo and in vitro data strongly suggest that omega 3 fatty acids might act as anti- rather than pro-oxidant in several cells such as vascular cells, hence diminishing inflammation, oxidative stress, and, in turn, the risk of atherosclerosis and degenerative disorders such as cardiovascular disease. |
| |
| Keywords: | Antioxidants Polyunsaturated fatty acids Free radicals Cardiovascular disease |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
