| 睫状神经营养因子对体外培养骨骼肌细胞的促增殖效应 |
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| 引用本文： | 邓小华. 睫状神经营养因子对体外培养骨骼肌细胞的促增殖效应[J]. 中国应用生理学杂志, 2000, 16(1): 59-63 |
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| 作者姓名： | 邓小华 |
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| 作者单位： | 第二军医大学基础医学部神经生物学教研室!上海200433(邓小华)，成都军区总医院(侍坚，蒋春雷，路长林) |
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| 摘 要： | 目的 :探讨睫状神经营养因子 (CNTF)对骨骼肌细胞的直接营养作用 ,从而为神经肌肉系统损伤和退行性病变的治疗提供新的思路。结果 :CNTF可以促进体外培养的L6 TG肌母细胞和新生SD大鼠原代骨骼肌细胞增殖。结论 :CNTF对体外骨骼肌细胞具有营养作用。CNTF的神经和肌肉双重营养性能使其可能在神经肌肉损伤和退行性病变的治疗上发挥重要作用。
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| 关 键 词： | 睫状神经营养因子 骨骼肌细胞 增殖 |
| 修稿时间： | : |
ENHANCING EFFECT OF CNTF ON THE PROLIFERATION OF SKELETAL MUSCLE CELLS IN CULTURE |
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| DENG Xiao hua ,SHI Jian ,JIANG Chun lei ,LU Chang lin. ENHANCING EFFECT OF CNTF ON THE PROLIFERATION OF SKELETAL MUSCLE CELLS IN CULTURE[J]. Chinese journal of applied physiology, 2000, 16(1): 59-63 |
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| Authors: | DENG Xiao hua SHI Jian JIANG Chun lei LU Chang lin |
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| Affiliation: | DENG Xiao hua 1,SHI Jian 2,JIANG Chun lei 2,LU Chang lin |
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| Abstract: | Aim: To study the direct trophic function of CNTF on muscle, and to explor new methods for nerve muscle injury and retrogression.Results:CNTF can enhance the proliferation of L6 TG cells and newborn SD rat primary skeletal muscle cells in culture.Conclusion:CNTF is of trophic function on muscle cells in culture. The neurotrophic and myotrophic effect of CNTF may play an important role in the treatment of nerve muscle injury and retrogression. |
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| Keywords: | cilliary neurotrophic factor(CNTF) skeletal muscle cells proliferation |
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