The <Emphasis Type="Italic">Mycobacterium marinum mel2</Emphasis> locus displays similarity to bacterial bioluminescence systems and plays a role in defense against reactive oxygen and nitrogen species |
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| Authors: | Selvakumar Subbian Parmod K Mehta Suat LG Cirillo Jeffrey D Cirillo |
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| Institution: | (1) Dept. Microbial and Molecular Pathogenesis, Texas A&M University Health Sciences Center - College of Medicine, 77843-1114 College Station, TX, USA |
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| Abstract: | Background Mycobacteria have developed a number of pathways that provide partial protection against both reactive oxygen species (ROS)
and reactive nitrogen species (RNS). We recently identified a locus in Mycobacterium marinum, mel2, that plays a role during infection of macrophages. The molecular mechanism of mel2 action is not well understood. |
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