Characterization of acute phase proteins and oxidative stress response to road transportation in the dog

Haptoglobin (Hp), serum amyloid A (SAA), C-reactive protein (CRP), white blood cells(WBC), reactive oxygen metabolites (ROMs), the antioxidant barrier (Oxy-adsorbent) andthiol groups of plasma compounds (SHp) were measured in ten dogs that had been transporteda distance of about 230 km within 2 h (experimental group) and in ten dogs that had notbeen subjected to road transportation (control group). Blood was collected via cephalicvenipuncture before road transportation (T0), after road transportation (T1), and morethan 6 (T6) and 24 (T24) hours after road transportation in the experimental group (GroupA) and at the same time points in the control group (Group B). The GLM (general linearmodel) Repeated Measures procedure showed a significant difference between the two groups(P<0.0001) and a significant rise (P<0.0001) inthe concentrations of Hp, SAA, CRP, WBC, ROMs, Oxy-adsorbent and SHp after roadtransportation in Group A, underlining that physiological and homeostatic mechanisms aremodified differently at various sampling times.