Growth of bifidobacteria and clostridia on human and cow milk saccharides |
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| Authors: | Rockova Sarka Rada Vojtech Marsik Petr Vlkova Eva Bunesova Vera Sklenar Jan Splichal Igor |
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| Institution: | aDepartment of Microbiology, Nutrition and Dietetics, Faculty of Agrobiology Food and Natural Resources, Czech University of Life Sciences, Kamycka 129, Prague 6, 165 21 Suchdol, Czech Republic;bLaboratory of Plant Biotechnologies, Joint Laboratory of Institute of Experimental Botany Academy of Sciences of the Czech Republic and Research Institute of Crop Production, Rozvojova 263, Prague 6, 165 02, Czech Republic;cDepartment of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Videnska 1083, Prague 142 20, Czech Republic;dDepartment of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Doly 183, Novy Hradek 549 22, Czech Republic |
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| Abstract: | For healthy infants, which were born normally and fully breastfed, the dominant component of the intestinal microflora are bifidobacteria. However, infants born by caesarean section possess clostridia as a dominant intestinal bacterial group. The aim of the present study was to determine whether bifidobacteria and clostridia are able to grow on human milk oligosaccharides (HMOs) and other carbon sources - lactose, cow milk (CM) and human milk (HM). Both bifidobacteria and clostridia grew on lactose and in CM. Bifidobacteria grew in HM and on HMOs. In contrast, 3 out of 5 strains of clostridia were not able to grow in HM. No clostridial strain was able to utilise HMOs. While both bifidobacterial strains were resistant to lysozyme, 4 out of 5 strains of clostridia were lysozyme-susceptible. It seems that HMOs together with lysozyme may act as prebiotic-bifidogenic compounds inhibiting intestinal clostridia. |
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| Keywords: | Bifidobacteria Clostridia Human milk Cow milk Milk saccharides |
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