Sequence and analysis of a plasmid-encoded mercury resistance operon from Mycobacterium marinum identifies MerH, a new mercuric ion transporter |
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| Authors: | Schué Mathieu Dover Lynn G Besra Gurdyal S Parkhill Julian Brown Nigel L |
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| Institution: | Mathieu Schué, Lynn G. Dover, Gurdyal. S. Besra, Julian Parkhill, and Nigel L. Brown |
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| Abstract: | In this study, we report the DNA sequence and biological analysis of a mycobacterial mercury resistance operon encoding a novel Hg2+ transporter. MerH was found to transport mercuric ions in Escherichia coli via a pair of essential cysteine residues but only when coexpressed with the mercuric reductase. |
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