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Changes in serum copper level during detoxification of acutely poisoned drug addicts
Authors:Wojciech Piekoszewski  Janusz Pach  Krystyna Sadlik  Lidia Winnik
Affiliation:(1) Institute of Forensic Research, 9 Westerplatte, 31-033 Krakow, Poland;(2) Department of Clinical Toxicology, Jagiellonian University, 2 Zlota Jesien, 31-826 Krakow, Poland;(3) Laboratory of Clinical Toxicology and Pharmacokinetics, Rydyger’s Hospital, 2 Zlota Jesien, 31-826 Krakow, Poland
Abstract:
Although it is known that drug addicts are a high-risk group for disruption of many homeostatic processes, little is know about changes in serum trace elements concentrations after taking the psychoactive substances. The aim of the study was to check the influence of the taking homemade heroin on serum level of copper. Blood samples were taken from 30 opiate addicts, and copper concentrations were measured by the means of atomic absorption spectrophotometry. The result of the study show that in the examined group, copper serum concentrations (1.35 mg/L) upon admission to the clinic were higher than in the control group (1.11 mg/L) but decreased during hospitalization (1.18 mg/L). There was no correlation between duration of stay at the hospital and changes in serum copper concentration.
Keywords:Opiates  homemade heroin  copper  serum
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