Versatile synthesis of Boc protected hydrazinoacetic acid and its application to the chemoselective ligation of TASP molecules |
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| Authors: | Banfi Damiano Mutter Manfred Patiny Luc |
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| Affiliation: | Institute of Chemical Sciences and Engineering, Federal Institute of Technology Lausanne, CH-1015 Lausanne, Switzerland. |
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| Abstract: | This paper describes a convenient synthesis of protected hydrazine derivatives, i.e. 1,2-bis-Boc-hydrazinoacetic acid, and its application for hydrazone ligation techniques in convergent template assembled synthetic protein (TASP) synthesis. |
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