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Smad3‐mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial–mesenchymal transition
Authors:Dan Du  Yoko Katsuno  Dominique Meyer  Erine H Budi  Si‐Han Chen  Hartmut Koeppen  Hongjun Wang  Rosemary J Akhurst  Rik Derynck
Institution:1. Department of Cell and Tissue Biology, University of California at San Francisco, San Francisco, CA, USA;2. Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California at San Francisco, San Francisco, CA, USA;3. Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA, USA;4. Department of Cellular and Molecular Pharmacology, Biophysics Graduate Program, University of California at San Francisco, San Francisco, CA, USA;5. Department of Research Pathology, Genentech Inc., South San Francisco, CA, USA;6. Department of Anatomy, University of California at San Francisco, San Francisco, CA, USA
Abstract:
Keywords:cancer cell dissemination  cancer drug resistance  epithelial stem cells  histone methylation  TGF‐β  signaling
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