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RNase H2, mutated in Aicardi‐Goutières syndrome,promotes LINE‐1 retrotransposition |
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| Authors: | Maria Benitez‐Guijarro Cesar Lopez‐Ruiz Žygimantė Tarnauskaitė Olga Murina Mahwish Mian Mohammad Thomas C Williams Adeline Fluteau Laura Sanchez Raquel Vilar‐Astasio Marta Garcia‐Canadas David Cano Marie‐Jeanne HC Kempen Antonio Sanchez‐Pozo Sara R Heras Andrew P Jackson Martin AM Reijns Jose L Garcia‐Perez |
| Affiliation: | 1. GENYO, Centro de Genómica e Investigación Oncológica: Pfizer ‐ Universidad de Granada ‐ Junta de Andalucía, Granada, Spain;2. MRC Human Genetics Unit, MRC, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, UK;3. Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain |
| Abstract: | |
| Keywords: | Aicardi‐Goutiè res Syndrome LINE‐1 retrotransposition RNase H2 RNA:DNA hybrids |